arginine + glycine => ornithine + guanidoacetate EC Number: 2.1.4.1 Glycine amindinotransferase, localized to the mitochondrial intermembrane space, catalyzes the reaction of arginine and glycine to form guanidinoacetate and ornithine. The active form of the enzyme is a dimer (Humm et al. 1997 {EMBO J]; Humm et al 1997 [Biochem J]). Its function in vivo has been confirmed by molecular and biochemical studies of patients deficient in the enzyme (Item et al. 2001). Pubmed11555793 Pubmed9148748 Pubmed9218780 Reactome Database ID Release 4371275 Reactome, http://www.reactome.org ReactomeREACT_396