creatine + ATP => phosphocreatine + ADP [CKB,CKM] Authored: D'Eustachio, P, 2007-07-18 14:33:15 Cytosolic creatine kinase catalyzes the reaction of creatine and ATP to form phosphocreatine and ADP. The active form of the enzyme is a dimer. Monomers of the cytosolic enzyme occur in two isoforms, B and M, so called because of their abundance in brain and muscle respectively. The enzyme is widely expressed in the body and many tissues express both isoforms. Both homo- (BB, MM) and heterodimers (BM) are catalytically active. EC Number: 2.7.3.2 Pubmed16981706 Reactome Database ID Release 43200318 Reactome, http://www.reactome.org ReactomeREACT_11156