aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] Cytosolic asparagine synthase (ASNS) catalyzes the reaction of aspartate, glutamine, and ATP to form asparagine, glutamate, AMP, and pyrophosphate. Studies of the recombinant protein expressed in E. coli suggest that the active form of the enzyme is a dimer (Van Heeke and Schuster 1989). EC Number: 6.3.5.4 Pubmed2564390 Reactome Database ID Release 4370599 Reactome, http://www.reactome.org ReactomeREACT_277