urocanate + H2O => 4-imidazolone-5-propionate Authored: D'Eustachio, P, 2003-06-24 00:00:00 Cytosolic urocanate hydratase (UROC1) catalyzes the hydrolysis of urocanate to form 4-imidazolone-5-propanoate. Human UROC1 was first identified in surveys of genes differentially expressed in hepatoblastoma (Yamamda et al. 2004). Recent biochemical and molecular studies of UROC1 protein and cDNA from a patient with urocanic aciduria has confirmed the function of UROC1 in vivo (Espinos et al. 2009). EC Number: 4.2.1.49 Edited: D'Eustachio, P, 2003-06-24 00:00:00 Pubmed15221005 Pubmed19304569 Reactome Database ID Release 4370903 Reactome, http://www.reactome.org ReactomeREACT_1166