dimeric phospho-ATM complex Dissociation of dimeric phospho-ATM complexes Authored: Matthews, L, 2003-12-10 03:30:00 Autophosphorylation of ATM results in the dissociation of the dimeric/multimeric ATM complex and initiation of ATM kinase activity. Autophosphorylation does not directly regulate ATM kinase activity. Instead, it is the resulting dissociation of ATM oligomers that allows substrates access to the ATM kinase domain. Pubmed12556884 Reactome Database ID Release 4383895 Reactome, http://www.reactome.org ReactomeREACT_1167 has a Stoichiometric coefficient of 2