Dietary tyramine is oxidatively deaminated to an aldehyde by MAOB Authored: Jassal, B, 2008-05-19 12:57:01 EC Number: 1.4.3.21 EC Number: 1.4.3.22 EC Number: 1.4.3.4 Edited: Jassal, B, 2008-05-19 12:57:01 Monoamine oxidases (MAO-A/B), present in the outer mitochondrial membrane, catalyze the oxidation of biogenic amines, releasing hydrogen peroxide (H2O2). H2O2 produced during the oxidative deamination of these amines appears to be involved in the progress of neurodegenerative disorders such as Parkinson disease, presumably via oxidative damage to the mitochondrial membrane. Pubmed4016087 Reactome Database ID Release 43141202 Reactome, http://www.reactome.org ReactomeREACT_1260 Reviewed: D'Eustachio, P, 2008-05-28 08:30:54