Glucuronidation of abacavir A member of the UDPGT (UDP-glucuronosyltransferase) enzyme family is thought to catalyze the reaction of abacavir and UDP-glucuronate to form UDP and abacavir-5'-glucuronate, one of the major forms in which abacavir is excreted from the body (McDowell et al. 1999; Ravitch and Moseley 2001). The specific UDPGT family enzyme family member or members that catalyze this reaction have not been identified. Authored: D'Eustachio, P, 2012-03-14 EC Number: 2.4.1.17 Edited: D'Eustachio, P, 2012-03-16 Pubmed10582871 Pubmed11678376 Reactome Database ID Release 432162099 Reactome, http://www.reactome.org ReactomeREACT_120923 Reviewed: Jassal, B, 2012-03-16 abacavir + UDP-glucuronate => abacavir 5'-glucuronide + UDP