Conversion of carbovir to carbovir monophosphate Authored: D'Eustachio, P, 2012-03-14 EC Number: 2.7.1.77 Edited: D'Eustachio, P, 2012-03-16 NT5C2 catalyzes the reaction of carbovir and IMP to form carbovir monophosphate and inosine (Johnson and Fridland 1989; Miller et al. 1992). The enzyme was originally identified as a high-Km soluble 5'-nucleotidase most active on IMP and GMP (Spychala et al. 1988). Its active form is a tetramer (Wallden et al. 2007). Pubmed1383219 Pubmed17405878 Pubmed2549385 Pubmed2848805 Reactome Database ID Release 432162066 Reactome, http://www.reactome.org ReactomeREACT_120749 Reviewed: Jassal, B, 2012-03-16 carbovir + IMP => carbovir monophosphate + inosine