Glycoprotein with galactose Addition of galactose by beta 4-galactosyltransferases Addition of a galactose residue on N-acetylglucosamine. The family of beta 4-galactosyltransferases is composed by at least six known members with different K(m) and acceptor specifities (Guo S et al, 2001) and probably originated by duplication (Lo NW et al, 1998). B4GALT1 is associated with Congenital Disorder of Glycosylation of type IId (Hansske B et al, 2002), and is expressed as two splicing isoforms of which only one is localizated in the Golgi system (Lopez LC et al, 1991; Schaub BE et al, 2006). B4GALT2 is key in the regulation of proteins involved in neuronal development (Sasaki N et <br>al, 2005). Authored: Dall'Olio, GM, 2009-11-10 EC Number: 2.4.1.38 Edited: Jassal, B, 2010-10-08 Pubmed11588157 Pubmed11901181 Pubmed15939404 Pubmed17021253 Pubmed1714903 Pubmed9597550 Reactome Database ID Release 43975919 Reactome, http://www.reactome.org ReactomeREACT_25178 Reviewed: Gagneux, P, 2010-11-18