Glycoprotein with GlcNAc in position 5 Addition of GlcNAc to position 5 by MGAT5 Authored: Dall'Olio, GM, 2009-11-10 EC Number: 2.4.1.155 Edited: Jassal, B, 2010-10-08 N-acetylglucosaminyltransferase (GnT)-V catalyzes the addition of GlcNAc beta 1,4 on the GlcNAc beta1,2 Man,alpha1,6 arm of complex type N-Glycans (Park C et al, 1999; Granowski M et al, 2000; Wang L et al, 2007). The activity of MGAT5 competes with MGAT3 (Pinho SS et al, 2009) and is associated with gastric cancer (Tian H et al, 2008) and multiple sclerosis (Brynedal B et al, 2010). Pubmed10395745 Pubmed10700233 Pubmed16924681 Pubmed18931531 Pubmed19403558 Pubmed20117844 Reactome Database ID Release 43975916 Reactome, http://www.reactome.org ReactomeREACT_25314 Reviewed: Gagneux, P, 2010-11-18