ub-FANCD- and ub-FANCI-bound chromatin FANCD and ub-FANCI-bound chromatin ubiquitin FANCD2 deubiquitination by USP1/UAF1 Authored: Matthews, L, 2009-05-02 17:26:55 Edited: Matthews, L, 2009-05-20 15:51:04 Pubmed15694335 Pubmed18082604 Reactome Database ID Release 43419525 Reactome, http://www.reactome.org ReactomeREACT_18350 Reviewed: Huang, TT, 2009-05-20 17:48:24 The FA pathway is negatively regulated through the USP1/UAF1 mediated deubiquitination of FANCD2 (Nijman et al., 2005) UAF1 forms a complex with and activates USP1 (Cohn et al., 2007).