dNTP newly synthesized DNA fragment damaged DNA substrate:nascent mRNA hybrid with dual incisions RFC Heteropentamer PCNA homotrimer RPA heterotrimer DNA Polymerase delta tetramer Repair synthesis for gap-filling by DNA pol delta in TC-NER At the beginning of this reaction, 1 molecule of 'dNTP', 1 molecule of 'RPA heterotrimer', 1 molecule of 'PCNA homotrimer', 1 molecule of 'RFC Heteropentamer', 1 molecule of 'DNA Polymerase delta tetramer', and 1 molecule of 'damaged DNA substrate:nascent mRNA hybrid with dual incisions' are present. At the end of this reaction, 1 molecule of 'RPA heterotrimer', 1 molecule of 'PCNA homotrimer', 1 molecule of 'RFC Heteropentamer', 1 molecule of 'newly synthesized DNA fragment ', 1 molecule of 'DNA Polymerase delta tetramer', and 1 molecule of 'damaged DNA substrate:nascent mRNA hybrid with dual incisions' are present.<br><br> This reaction takes place in the 'nucleus' and is mediated by the 'delta DNA polymerase activity' of 'DNA Polymerase delta tetramer'.<br> EC Number: 2.7.7.7 Reactome Database ID Release 43110305 Reactome, http://www.reactome.org ReactomeREACT_1196