uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid Authored: D'Eustachio, P, 2005-04-04 21:01:34 EC Number: 3.1 Edited: D'Eustachio, P, 0000-00-00 00:00:00 Pubmed14734546 Reactome Database ID Release 43162729 Reactome, http://www.reactome.org ReactomeREACT_1978 The fatty acid group added to inositol in the fourth step of GPI biosynthsis is removed from GPI-conjugated uPAR. This hydrolysis event occurs in the endoplasmic reticulum and appears to be associated with efficient transport of the conjugated protein from the endoplasmic reticulum to the Golgi apparatus (Tanaka et al. 2004).