Fructose 6-phosphate isomerizes to Mannose 6-phosphate Authored: Dall'Olio, GM, 2009-11-10 EC Number: 5.3.1.8 Edited: Jassal, B, 2010-03-01 Mannose-6-phosphate isomerase (MPI) converts Fructose 6-phosphate to Mannose 6-phosphate (Proudfoot AE et al, 1994). Defects in this gene are associated with congenital disorder of glycosylation type 1B (CDG1B). Oral administration of mannose is an efficient therapy against this defect (Schollen E et al, 2000). Pubmed10980531 Pubmed8307007 Reactome Database ID Release 43532549 Reactome, http://www.reactome.org ReactomeREACT_22388 Reviewed: Gagneux, P, 2010-04-16