Addition of a fourth and fifth mannose to the N-glycan precursor by ALG11 A fourth mannose is added to the N-glycan precursor by ALG11. The addition of the fifth mannose, also by ALG11, is the last step occurring on the cytosolic side of the ER membrane (Cipollo JF et al, 2001). Both these reactions are alpha1,2 mannose additions. There are no known associations between ALG11 and CDG disorders to date. Authored: Dall'Olio, GM, 2009-11-10 Edited: Jassal, B, 2009-11-10 Pubmed11278778 Reactome Database ID Release 43446187 Reactome, http://www.reactome.org ReactomeREACT_22156 Reviewed: Gagneux, P, 2010-04-16 has a Stoichiometric coefficient of 2