PathwayStep1370 PathwayStep1386 Expression of CPT1A Expression of NPAS2 Expression of BMAL1 (ARNTL). Expression of NR1D1 (REV-ERBA) Expression of SREBF1 (SREBP1) PathwayStep5956 PathwayStep5973 PathwayStep5940 RORA Activates Circadian Expression As inferred from mouse, RORA binds ROR elements (ROREs) in DNA and recruits the coactivators PPARGC1A (PGC-1alpha) and p300 (EP300, a histone acetylase) to activate transcription. Authored: May, B, 2011-06-22 Edited: May, B, 2011-06-22 Pubmed7926749 Reactome Database ID Release 431368082 Reactome, http://www.reactome.org ReactomeREACT_118659 Reviewed: Delaunay, F, 2012-01-28