PathwayStep1389 Expression of PPARA Expression of FACTOR VII (F7) Expression of DEC2 (BHLHE41, BHLHB3) Expression of NOCTURNIN Expression of AVP Expression of DEC1 (BHLHE40, BHLHB2) Expression of DBP Expression of CRYPTOCHROME-2 Expression of CRYPTOCHROME-1 Expression of NAMPT (NamPRT, PBEF, Visfatin) Expression of PAI-1 Expression of NR1D1 (REV-ERBA) Expression of PERIOD-2 Expression of PERIOD-1 PathwayStep5956 PathwayStep5954 PathwayStep5955 PathwayStep5952 PathwayStep5953 PathwayStep5949 PathwayStep5944 PathwayStep5946 PathwayStep5945 PathwayStep5948 PathwayStep5947 PathwayStep5950 PathwayStep5951 BMAL1:CLOCK/NPAS2 Activates Circadian Expression As inferred from mouse, BMAL1:CLOCK and BMAL1:NPAS2 heterodimers bind to sequence elements (E boxes) in the promoters of target genes and enhance transcription (Gekakis et al. 1998, reviewed in Munoz and Baler 2003). Authored: May, B, 2011-06-22 Edited: May, B, 2011-06-22 Pubmed12868535 Pubmed9616112 Reactome Database ID Release 431368108 Reactome, http://www.reactome.org ReactomeREACT_111118 Reviewed: Albrecht, U, 2010-06-23 Reviewed: D'Eustachio, P, 2009-05-26 22:13:22 Reviewed: Delaunay, F, 2010-06-23 Reviewed: Hirota, T, 2010-06-23 Reviewed: Kay, SA, 2010-06-23