PathwayStep6164 PathwayStep6165 PathwayStep6166 PathwayStep6167 PathwayStep6168 PathwayStep6169 PathwayStep6160 PathwayStep6161 PathwayStep6162 PathwayStep6163 NCAM1 interactions Authored: Garapati, P V, 2009-02-24 10:31:41 Edited: Garapati, P V, 2009-02-24 10:31:41 Pubmed15662836 Pubmed18607724 Reactome Database ID Release 43419037 Reactome, http://www.reactome.org ReactomeREACT_18312 Reviewed: Maness, PF, Walmod, PS, 2009--0-5- The neural cell adhesion molecule, NCAM1 is generally considered as a cell adhesion mediator, but it is also considered to be a signal transducing receptor molecule. NCAM1 is involved in multiple cis- and trans-homophilic interactions. It is also involved in several heterophilic interactions with a broad range of other molecules, thereby modulating diverse biological phenomena including cellular adhesion, migration, proliferation, differentiation, survival and synaptic plasticity. Interaction of NCAM1 with agrin Interaction of NCAM1 with contactin-2 NCAM1 binds to ATP Interaction of NCAM1:GFRalpha-1 with GDNF Interaction of NCAM1 with Neurocan Interaction of NCAM1 with collagens Interaction of NCAM1 with Major prion protein (PrP) Interaction of NCAM1 with GFRalpha-1 Polysialylation of NCAM1 NCAM1 interacts with T- and L-type VDCC