L1:NCAM1 complex L1 and NCAM1 engaged in cis-interaction Authored: Garapati, P V, 2008-07-30 10:22:58 Edited: Garapati, P V, 2008-07-30 10:22:58 L1 and NCAM1 co-expressed on a single cell interact with each other via the fourth Ig domain of NCAM1 and the oligomannose type oligosaccharides carried by L1. This interaction has synergetic effects on L1-mediated cell aggregation and adhesion, a phenomenon referred to as 'assisted homophilic L1-L1 trans-binding'. Pubmed10611478 Pubmed2295682 Pubmed8509458 Reactome Database ID Release 43374681 Reactome, http://www.reactome.org ReactomeREACT_22231 Reviewed: Maness, PF, 2010-02-16