PathwayStep5149 PathwayStep5150 PathwayStep5151 PRDM4 inhibits cyclin E transcription PRDM4 translocates to the nucleus PRDM4 (SC1) binds to p75NTR p75NTR negatively regulates cell cycle via SC1 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Edited: Jassal, B, 2008-05-20 12:26:36 GENE ONTOLOGYGO:0045786 Pubmed12371150 Reactome Database ID Release 43193670 Reactome, http://www.reactome.org ReactomeREACT_13695 Reviewed: Chao, MV, 2008-05-28 09:46:01 Reviewed: Friedman, WJ, 2008-05-20 12:23:46 SC1 (Schwann Cell factor 1; also called PR domain zinc finger protein 4, PRDM4) interacts with an NGF:p75NTR complex and signals cell cycle arrest by regulating the levels of cyclin E.