PathwayStep5313 PathwayStep5315 PathwayStep5314 PathwayStep5317 PathwayStep5316 PathwayStep5319 PathwayStep5318 PathwayStep5320 PKC alpha interacts with and phosphorylates KIT Phosphorylation of APS Interaction of APS and p-KIT SOCS1 as a regulator of KIT signaling Interaction of SHP1 and KIT Downregulation of c-Kit signaling by SOCS6 Recruitment of CBL to KIT LNK binds to p-KIT and inhibit downstream signaling Regulation of KIT signaling Authored: Garapati, P V, 2011-07-11 Edited: Garapati, P V, 2011-07-11 Pubmed10582339 Pubmed16483568 Reactome Database ID Release 431433559 Reactome, http://www.reactome.org ReactomeREACT_111225 Reviewed: Rönnstrand, L, 2011-08-22 SCF induced proliferation is negatively regulated by various proteins including SHP1, PKC, CBL, SOCS1, SOCS6 and LNK.