Syntaxin fragment Syntaxins BoNT Light Chain Type C1 cleaves Syntaxin Authored: Krupa, S, Gopinathrao, G, 2006-06-15 10:36:11 EC Number: 3.4.24 Edited: Gopinathrao, G, 2006-06-15 22:12:29 Pubmed8611567 Reactome Database ID Release 43181567 Reactome, http://www.reactome.org ReactomeREACT_11195 Reviewed: Ichtchenko, K, 2007-08-03 18:17:25 Syntaxins are involved in the localization (docking) of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxin 1A interacts with SNAP-25 in forming t-SNARE part of SNARE complex. BoNT Type C specifically cleaves Syntaxin 1A although a broader target spectrum is suspected.