pFAK (391) bound to NCAM1:pFyn NCAM1 complexed with pFyn-Y420 Recruitment of FAK to NCAM1:Fyn in lipid rafts Authored: Garapati, P V, 2009-02-24 10:31:15 EC Number: 2.7.10 Edited: Garapati, P V, 2009-02-24 10:58:20 Fyn activation leads to the recruitment and activation of the non-receptor tyrosine kinase FAK. Once recruited to Fyn, FAK undergoes autophosphorylation on tyrosine 397. This tyrosine allows the binding of SH2 domain containing proteins. Pubmed9079653 Reactome Database ID Release 43391865 Reactome, http://www.reactome.org ReactomeREACT_18333 Reviewed: Maness, PF, Walmod, PS, 2009--0-5-