(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) (Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) Adenylate cyclase increases the GTPase activity of Gi alpha Authored: Le Novere, N, Jassal, B, 2004-03-31 12:22:05 EC Number: 3.6.5.1 EC Number: 3.6.5.2 EC Number: 3.6.5.3 EC Number: 3.6.5.4 Edited: Jassal, B, 2008-11-06 10:17:49 G proteins can deactivate themselves via their intrinsic GTPase activity, which hydrolyzes GTP to GDP. Effectors such as adenylate cyclase can increase the G protein GTPase rate, acting like GTPase-activating proteins (GAPs). Pubmed7937899 Reactome Database ID Release 43170686 Reactome, http://www.reactome.org ReactomeREACT_15495 Reviewed: Castagnoli, L, 2008-11-06 12:55:54