Receptors CCR3, 4 and 5 bind CCL5 ligand Receptors CCR1, 2 and 8 bind CCL16 ligand Receptor CCR11 binds CCL19, CCL21 & CCL25 Receptor CCBP2 binds most inflammatory CC chemokines Receptor CCR10 binds CCL27 and 28 ligands Receptor CCR6 binds CCL20 ligand Receptor CX3C1 binds CX3CL1 Receptor CCR9 binds CCL25 ligand Receptor CXCR1 binds CXCL6 and CXCL8 ligands Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta Receptor CCR7 binds CCL19 and 21 ligands Receptor CXCR6 binds CXCL16 ligand Receptor CXCR2 binds ligands CXCL1 to 7 Receptor CXCR3 binds ligands CXCL9 to 11 Receptors CXCR4 and 7 bind CXCL12 ligand CXCR5 binds CXCL13 PathwayStep5585 PathwayStep5586 PathwayStep5581 PathwayStep5582 PathwayStep5583 PathwayStep5584 PathwayStep5580 PathwayStep5579 PathwayStep5578 PathwayStep5572 PathwayStep5573 PathwayStep5571 PathwayStep5576 PathwayStep5577 PathwayStep5574 PathwayStep5575 Chemokine receptors bind chemokines Authored: Jassal, B, 2008-11-07 12:17:32 Chemokine receptors are cytokine receptors found on the surface of certain cells, which interact with a type of cytokine called a chemokine. Following interaction, these receptors trigger a flux of intracellular calcium which leads to chemotaxis. Chemokine receptors are divided into different families, CXC chemokine receptors, CC chemokine receptors, CX3C chemokine receptors and XC chemokine receptors that correspond to the 4 distinct subfamilies of chemokines they bind. Pubmed10807766 Pubmed11544102 Pubmed15578986 Reactome Database ID Release 43380108 Reactome, http://www.reactome.org ReactomeREACT_15344