Zinc is an agonist of GPR39 N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine G-protein coupled bile acid receptor binds lithocholic acid Niacin receptors bind niacin GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors Melatonin receptors can bind melatonin PAF receptor binds platelet activating factor Cannabinoid receptors can bind cannabinoids PathwayStep5629 PathwayStep5700 PathwayStep5702 PathwayStep5701 PathwayStep5703 PathwayStep5648 PathwayStep5653 PathwayStep5667 PathwayStep5690 PathwayStep5693 PathwayStep5698 PathwayStep5685 PathwayStep5684 PathwayStep5687 PathwayStep5686 PathwayStep5699 Class A/1 (Rhodopsin-like receptors) Authored: Jassal, B, 2008-07-03 10:57:39 Edited: D'Eustachio, P, 2008-09-01 11:58:31 Pubmed12429062 Pubmed16902930 Reactome Database ID Release 43373076 Reactome, http://www.reactome.org ReactomeREACT_14828 Reviewed: Bockaert, J, 2008-09-01 12:04:13 Rhodopsin-like receptors (class A/1) are the largest group of GPCRs and are the best studied group from a functional and structural point of view. They show great diversity at the sequence level and thus, can be subdivided into 19 subfamilies (Subfamily A1-19) based on a phylogenetic analysis (Joost P and Methner A, 2002). They represent members which include hormone, light and neurotransmitter receptors and encompass a wide range of functions including many autocrine, paracrine and endocrine processes. Peptide ligand-binding receptors Hormone ligand-binding receptors Amine ligand-binding receptors Lysosphingolipid and LPA receptors Opsins Free fatty acid receptors Nucleotide-like (purinergic) receptors Eicosanoid ligand-binding receptors