Trace amine-associated receptors can bind trace amines PathwayStep5632 PathwayStep5647 PathwayStep5646 PathwayStep5635 PathwayStep5638 PathwayStep5642 Serotonin receptors Dopamine receptors Histamine receptors Muscarinic acetylcholine receptors Adrenoceptors Amine ligand-binding receptors Authored: Jassal, B, 2008-08-21 14:55:38 Edited: Jassal, B, 2008-08-21 14:55:38 Pubmed11459929 Pubmed15148138 Pubmed17073660 Pubmed17897004 Pubmed7938162 Pubmed9311023 Reactome Database ID Release 43375280 Reactome, http://www.reactome.org ReactomeREACT_16983 Reviewed: D'Eustachio, P, 2009-03-02 09:24:35 The class A (rhodopsin-like) GPCRs that bind to classical biogenic amine ligands are annotated here. The amines involved (acetylcholine, adrenaline, noradrenaline, dopamine, serotonin and histamine) can all act as neurotransmitters in humans. The so-called 'trace amines', used when referring to p-tyramine, beta-phenylethylamine, tryptamine and octopamine, can also bind to recently-discovered GPCRs.