Corticotropin-releasing hormone receptor can bind CRH Patched binds Smoothened Parathyroid hormone receptor can bind parathyroid hormone CD97 binds CD55 EGF-TM7 receptors bind chondroitin sulphate Frizzled receptors bind Wnts PathwayStep5709 PathwayStep5720 PathwayStep5716 PathwayStep5717 PathwayStep5710 PathwayStep5718 PathwayStep5719 PathwayStep5721 Calcitonin-like ligand receptors Glucagon-type ligand receptors Class B/2 (Secretin family receptors) Authored: Jassal, B, 2008-07-14 12:08:56 Edited: Jassal, B, 2008-07-14 12:08:56 Pubmed11790261 Reactome Database ID Release 43373080 Reactome, http://www.reactome.org ReactomeREACT_18372 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22 This family is known as Family B (secretin-receptor family, family 2) G-protein-coupled receptors. Family B GPCRs include secretin, calcitonin, parathyroid hormone/parathyroid hormone-related peptides and vasoactive intestinal peptide receptors; all of which activate adenylyl cyclase and the phosphatidyl-inositol-calcium pathway (Harmar AJ, 2001).