PathwayStep584 TP receptor can bind thromboxane IP receptor can bind prostacyclin FP receptor can bind PGF2-alpha DP2 receptor can bind PGD2 DP1 receptor can bind PGD2 EP1 receptor can bind PGE2 EP2 and EP4 receptors can bind PGE2 EP3 receptor can bind PGE2 PathwayStep5654 PathwayStep5659 PathwayStep5656 PathwayStep5655 PathwayStep5658 PathwayStep5657 PathwayStep5660 Prostanoid ligand receptors Authored: Jassal, B, 2009-04-02 10:56:26 Edited: Jassal, B, 2009-04-02 10:56:26 Fatty acid cyclo-oxygenase (COX) converts arachidonic acid to prostaglandin H2 (PGH2) from which the prostanoids PGD2, PGE2, PGF2alpha, PGI2 (prostacyclin) and thromboxane A2 (TXA2) are derived. Based on the agonist potencies, five prostanoid receptors are recognized and correspondingly named DP, EP, FP, IP and TP receptors (Coleman RA et al, 1994). Additionally, EP receptors contains four subtypes, termed EP1, EP2, EP3 and EP4; the DP receptor also has two subtypes, DP1 and DP2 (CRTH2). Pubmed7938166 Reactome Database ID Release 43391908 Reactome, http://www.reactome.org ReactomeREACT_18425 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22