P2Y2 receptor binds ATP and UTP P2Y1 receptor can bind to ADP P2Y10 receptor can bind to LPA P2Y9 receptor can bind to LPA P2Y6 receptor can bind to UDP P2Y5 receptor can bind to LPA P2Y4 receptor can bind to UTP The UDP/CysLT (P2Y17) receptor can bind UTP P2Y14 receptor can bind to UDP-glucose P2Y13 receptor can bind ADP P2Y12 receptor can bind to ADP P2Y11 receptor can bind to ATP PathwayStep5669 PathwayStep5668 PathwayStep5675 PathwayStep5676 PathwayStep5673 PathwayStep5674 PathwayStep5671 PathwayStep5672 PathwayStep5670 PathwayStep5677 PathwayStep5678 PathwayStep5679 P2Y receptors Authored: Jassal, B, 2009-04-14 09:13:21 Edited: Jassal, B, 2009-04-14 09:13:21 P2Y receptors are a family of purinergic receptors, G protein-coupled receptors stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP-glucose. To date, 12 P2Y receptors have been cloned in humans (Abbracchio MP et al, 2006; Fischer W and Krugel U, 2007). P2Y receptors are present in almost all human tissues where they exert various biological functions based on their G-protein coupling. Purine nucleotides are involved in a large number of intermediate metabolic pathways, taking part as substrates, products or allosteric factors. Pubmed16968944 Pubmed17979698 Reactome Database ID Release 43417957 Reactome, http://www.reactome.org ReactomeREACT_18289 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22