Oxoeicosanoid receptor can bind oxoeicosanoid PathwayStep5666 PathwayStep5665 PathwayStep5661 Prostanoid ligand receptors Leukotriene receptors Eicosanoid ligand-binding receptors Authored: Jassal, B, 2009-02-25 13:56:29 Edited: Jassal, B, 2009-02-25 13:56:29 Eicosanoids, derived from polyunsaturated 20-carbon fatty acids, are paracrine and autocrine regulators of inflammation, smooth muscle contraction, and blood coagulation. The actions of eicosanoids are mediated by eicosanoid receptors, most of which are GPCRs. There are four types of eicosanoid GPCRs in humans; leukotriene, lipoxin (Brink C et al, 2003), prostanoid (Coleman RA et al, 1994) and oxoeicosanoid (Brink C et al, 2004) receptors. Pubmed12615958 Pubmed15001665 Pubmed7938166 Reactome Database ID Release 43391903 Reactome, http://www.reactome.org ReactomeREACT_18352 Reviewed: D'Eustachio, P, 2009-05-29 07:44:22