NMDA receptor complex NMDA receptor ligand complex Glutamate binding to NMDA receptor Authored: Mahajan, SS, 2009-10-29 Edited: Gillespie, ME, 2009-06-02 00:56:21 NMDA receptors require binding of two ligands; the agonist, glutamate and co-agonist, glycine. The N terminal extracellular ligand binding domain in NR1 subunits binds co-agonist glycine and the N terminal extracellular ligand binding domain in NR2 binds glutamate. Pubmed8665664 Reactome Database ID Release 43432172 Reactome, http://www.reactome.org ReactomeREACT_20601 Reviewed: Tukey, D, 2009-11-17