OAT1-3 transport organic anions with antiport of dicarboxylic acids OAT2 and OAT4 mediate transport of sulphate conjugates URAT1 regulates urate levels in blood with exchange for organic anions PathwayStep4945 PathwayStep4946 PathwayStep4947 Organic anion transport Authored: Jassal, B, 2010-03-25 Edited: Jassal, B, 2010-03-25 Organic anion transporters (OATs) mediate the renal absorption and excretion of a broad range of endogenous substrates and anionic drugs such as diuretics and NSAIDs. Five members belong to these polyspecific transporters (OAT1-4 and URAT1) and are predominantly expressed in the kidney (Koepsell H and Endou H, 2004; Rizwan AN and Burckhardt G, 2007; Ahn SY and Bhatnagar V, 2008). Pubmed12883891 Pubmed17245646 Pubmed18695391 Reactome Database ID Release 43561048 Reactome, http://www.reactome.org ReactomeREACT_22310 Reviewed: He, L, 2010-05-10