Nuclear Pore Complex (NPC) Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP Translocation of nuclear RNA transport complex to cytoplasm Authored: Matthews, L, Rice, AP, 2005-07-27 00:00:00 Crm1 is a nucleocytoplasmic transport factor that is believed to interact with nucleoporins facilitating docking of the RRE-Rev-CRM1-RanGTP complex to the nuclear pore and the translocation of the complex across the nuclear pore complex (see Cullen 1998) Crm1 has been found in complex with two such nucleoporins, CAN/Nup214 and Nup88 which have been shown to be components of the human nuclear pore complex (Fornerod et al., 1997). Edited: Matthews, L, 2006-07-13 06:31:19 Pubmed11836381 Pubmed7958838 Pubmed9049309 Pubmed9323133 Pubmed9791012 Reactome Database ID Release 43165047 Reactome, http://www.reactome.org ReactomeREACT_6340 Reviewed: Kumar, A, 2007-01-31 22:47:49