CD28:Nef:Clathrin-coated Pit Adapter Protein CD28:Nef:Clathrin-coated Pit Adapter Protein Complex Internalization of Nef:CD28:Clathrin-Coated Pit Adapter Protein Complex Authored: Gillespie, ME, 2007-07-25 19:42:36 Once Nef has induced endocytosis of CD28, CD28 containing vesicles are targeted for lysosomal degradation. Pubmed11285224 Reactome Database ID Release 43167637 Reactome, http://www.reactome.org ReactomeREACT_11164 Reviewed: Skowronski, J, 2007-08-07 14:33:41