(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine
Authored: D'Eustachio, P, 2010-07-07
EC Number: 2.6.1.40
Edited: D'Eustachio, P, 2010-07-07
Mitochondrial AGXT2 tetramer catalyzes the reaction of (R)-3-aminoisobutyric acid and pyruvate to form 2-methyl-3-oxopropanoate and alanine. While the human mitochondrial AGXT2 enzyme has been characterized experimentally in other respects (Rodionov et al. 2010), its ability to catalyze this transamination reaction is inferred from the properties of its rat homologue.
Pubmed20018850
Reactome Database ID Release 43909780
Reactome, http://www.reactome.org
ReactomeREACT_25332
Reviewed: Jassal, B, 2010-11-09