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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/chebi#has_parent_hydride -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/chebi#has_parent_hydride"/>
    


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    <!-- http://purl.obolibrary.org/obo/CHEBI_139590 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_139590">
        <rdfs:label>primary alpha-hydroxy ketone</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_16827 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_16827">
        <rdfs:label>corticosterone</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_139590"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24261"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35344"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35346"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_36885"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47909"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_61313"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/chebi#has_parent_hydride"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_8386"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_75771"/>
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        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77746"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasExactSynonym>corticosterone</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>(11beta)-11,21-dihydroxypregn-4-ene-3,20-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Reichstein&#39;s substance H</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Kendall&#39;s compound B</oboInOwl:hasRelatedSynonym>
        <ns4:IAO_0000115>A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>KEGG:C02140</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:19131</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>HMDB:HMDB0001547</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>11beta,21-Dihydroxy-4-pregnene-3,20-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>MetaCyc:CORTICOSTERONE</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:57911</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>PDBeChem:C0R</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:16827</oboInOwl:id>
        <oboInOwl:hasDbXref>LINCS:LSM-5814</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>CHEBI:14022</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>CORTICOSTERONE</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Corticosterone</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>11beta,21-dihydroxypregn-4-ene-3,20-dione</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>CHEBI:41361</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>CHEBI:3891</oboInOwl:hasAlternativeId>
        <oboInOwl:hasRelatedSynonym>17-deoxycortisol</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>Corticosterone</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>11beta,21-dihydroxyprogesterone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24261 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24261">
        <rdfs:label>glucocorticoid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35344 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35344">
        <rdfs:label>21-hydroxy steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35346 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35346">
        <rdfs:label>11beta-hydroxy steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_36885 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_36885">
        <rdfs:label>20-oxo steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_47909 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_47909">
        <rdfs:label>3-oxo-Delta(4) steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_61313 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_61313">
        <rdfs:label>C21-steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_75771 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_75771">
        <rdfs:label>mouse metabolite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_77746 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_77746">
        <rdfs:label>human metabolite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_8386 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_8386">
        <rdfs:label>pregnane</rdfs:label>
    </Class>
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