has role 3-hydroxy-3-methylglutaric acid CHEBI:18746 MetaCyc:CPD-547 CHEBI:391 3-Hydroxy-3-methylpentanedioic acid KEGG:D04897 A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura. PDBeChem:MAH CHEBI:1524 meglutol 3-HYDROXY-3-METHYL-GLUTARIC ACID meglutolum (S)-3-Hydroxy-3-methylglutaric acid beta-hydroxy-beta-methylglutaric acid DrugBank:DB04377 HMDB:HMDB0000355 CHEBI:11044 CHEBI:16831 CHEBI:43804 (S)-Meglutol beta-Hydroxy-beta-methylglutaric acid 3-hydroxy-3-methylpentanedioic acid KNApSAcK:C00001187 Dicrotalic acid KEGG:C03761 CHEBI:20043 glutaric acid tertiary alcohol 3-hydroxy-3-methylglutarate(1-) antimetabolite EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor dicarboxylic acid anticholesteremic drug 3-hydroxy carboxylic acid plant metabolite human metabolite