Autosomal dominant inheritance SNOMEDCT_US:263681008 UMLS:C0443147 HP:0001456 Autosomal dominant HP:0001447 HP:0001415 HP:0001448 HP:0000006 monoallelic_autosomal Autosomal dominant form Autosomal dominant type A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele. HP:0001463 HP:0001452 HP:0001455 HP:0001451 Mendelian inheritance