Corneal crystals HP:0007760 Refractile, glittering, or needle-shaped particles said to resemble crystals and located within the corneal epithelium and/or stroma, visible on slit-lamp examination, resulting from the focal accumulation of lipid, protein, or other metabolic material. HP:0000531 The differential diagnosis includes Schnyder corneal dystrophy, cystinosis, immunoglobulin/paraprotein crystals, infectious crystalline keratopathy, and drug-induced crystalline deposits. Crystalline deposits are typically ascertained by slit lamp examination. Corneal deposits Opacification of the corneal stroma