has part has part characteristic of inheres in has modifier growth hormone secretion Elevated circulating growth hormone concentration SNOMEDCT_US:74107003 Somatotropin excess Growth hormone excess Disorder resulting from excess pituitary gland production of growth hormone (hGH). Acromegaly is a condition resulting from overproduction of growth hormone by the pituitary gland in persons with closed epiphyses, and consists chiefly in the enlargement of the distal parts of the body. The circumference of the skull increases, the nose becomes broad, the tongue becomes enlarged, the facial features become coarsened, the mandible grows excessively, and the teeth become separated. The fingers and toes grow chiefly in thickness. HP:0000845 HP:0008856 UMLS:C0235986 UMLS:C0001206 Elevated circulating somatotropin concentration Hyperpituitarism Abnormal circulating growth hormone concentration abnormal increased rate