has part has part characteristic of part of inheres in part of has modifier Abnormality of the endocrine system Abnormality of the hypothalamus-pituitary axis HP:0000864 HP:0000844 UMLS:C4025819 HP:0000838 Abnormality of the pituitary gland (also known as hypophysis), which is an endocrine gland that protrudes from the bottom of the hypothalamus at the base of the brain. The pituitary gland secretes the hormones ACTH, TSH, PRL, GH, endorphins, FSH, LH, oxytocin, and antidiuretic hormone. The secretion of hormones from the anterior pituitary is under the strict control of hypothalamic hormones, and the posterior pituitary is essentially an extension of the hypothalamus, so that hypothalamus and pituitary gland may be regarded as a functional unit. quality abnormal hypothalamus-pituitary axis