Xanthomatosis Eruptive xanthomas SNOMEDCT_US:238952003 Eruptive xanthomas occur in the setting of chylomicronemia and hypertriglyceridemia. HP:0001013 UMLS:C0221252 Eruptive xanthomas are yellow-orange-to-red-brown papules that are often surrounded by an erythematous halo. They appear in crops on the buttocks, extensor surfaces of the extremities, and flexural creases. Acutely, variable amounts of pruritus and pain occur.