Papilledema The borders of the optic disc are normally clear and well defined upon fundoscopic examination. Papilledema is optic disc swelling that can lead to the blurring of optic margins and elevation of optic disc. HP:0001085 HP:0001130 SNOMEDCT_US:248487006 SNOMEDCT_US:73221001 UMLS:C0030353 Papillitis Papilledema refers to edema (swelling) of the optic disc secondary to any factor which increases cerebral spinal fluid pressure. SNOMEDCT_US:423341008 Abnormal optic disc morphology