<?xml version="1.0"?>
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     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:hp="http://purl.obolibrary.org/obo/hp#"
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/hp#hposlim_core"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

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        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
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        <rdfs:label>has modifier</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/HP_0001363 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0001363">
        <rdfs:label>Craniosynostosis</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002166"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
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                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
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                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002683"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0011329"/>
        <oboInOwl:hasDbXref>UMLS:C0010278</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Early fusion of cranial sutures</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0005448</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>Fyler:4336</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Premature suture closure</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>SNOMEDCT_US:57219006</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>HP:0008492</oboInOwl:hasAlternativeId>
        <oboInOwl:id>HP:0001363</oboInOwl:id>
        <oboInOwl:hasRelatedSynonym>Craniostenosis</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasAlternativeId>HP:0001365</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>HP:0005467</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Cranial suture synostosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasAlternativeId>HP:0004494</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>Premature closure of cranial sutures</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>UMLS:C0235942</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>Craniosynostosis refers to the premature closure of the cranial sutures. Primary craniosynostosis refers to the closure of one or more sutures due to abnormalities in skull development, and secondary craniosynostosis results from failure of brain growth.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>Craniosyostosis</oboInOwl:hasExactSynonym>
        <rdfs:comment>Skull deformity caused by the premature closure of the cranial sutures. Craniostenosis is a deformity of the skull caused by craniosynostosis, with consequent cessation of skull growth.</rdfs:comment>
        <oboInOwl:hasAlternativeId>HP:0005457</oboInOwl:hasAlternativeId>
        <oboInOwl:hasBroadSynonym>Deformity of the skull</oboInOwl:hasBroadSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/hp#hposlim_core"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0002683 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0002683">
        <rdfs:label>Abnormal calvaria morphology</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0011329 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0011329">
        <rdfs:label>Abnormality of cranial sutures</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0002166 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0002166">
        <rdfs:label>premature closure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000982 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000982">
        <rdfs:label>skeletal joint</rdfs:label>
    </Class>
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