Cor pulmonale Cor pulmonale refers to a change in structure and function of the right ventricle of the heart as a result of a pulmonary disorder, generally resulting in right ventricular hypertrophy. SNOMEDCT_US:274096000 Right-sided heart failure resulting from chronic hypertension in the pulmonary arteries and right ventricle. SNOMEDCT_US:83291003 HP:0001648 UMLS:C0034072 Abnormal right ventricle morphology