has part has part characteristic of inheres in has modifier Abnormal aortic morphology Coarctation of aorta Coarctation of the aorta Aortic coarctation HP:0001680 Coarctation of the aorta is a narrowing or constriction of a segment of the aorta. Coarctation refers to a narrowing of the lumen of a vessel producing an obstruction to flow. Coarctation can occur in any region of the aorta. Coarctation of the aorta is often a discrete obstruction commonly located in the descending thoracic aorta. More specifically, it is usually located in the juxtaductal position immediately distal to the left-subclavian artery in a left-sided arch. The hallmark clinical finding in coarctation of the aorta is hypertension proximal to the lesion, with diminished blood pressure distal to the obstruction. Consequently, clinical diagnosis can be made by the presence of diminished lower extremity pulses, differences in timing between upper extremity central pulses (often brachial) and lower extremity central pulses (often femoral), or the presence of a supine arm-leg blood pressure gradient. Narrowing of aorta Narrowing of the aorta UMLS:C0003492 SNOMEDCT_US:7305005 abnormal constricted aorta