Megaloblastic anemia HP:0001889 Anemia characterized by the presence of erythroblasts that are larger than normal (megaloblasts). Megaloblastic anaemia SNOMEDCT_US:53165003 HP:0004858 Megaloblastic anemia can result from folic acid deficiency or vitamin B12 deficiency. Folate deficiency leads to an impairment of DNA synthesis such that the cell cycle cannot progress from the G2 growth stage to the mitosis stage, in turn leading to continuing cell growth without division, which presents as macrocytosis. UMLS:C0002888 Macrocytic anemia