Alkalosis Depletion of acid or accumulation base in the body fluids. SNOMEDCT_US:21420006 UMLS:C0002063 When describing acid-base abnormalities, acidosis and alkalosis refer to physiological processes that lower or raise the pH, respectively, while acidemia and alkalemia simply describe the state of an abnormal blood pH. This distinction is important: a patient with acidemia could have both a respiratory and metabolic acidosis as well as a concurrent metabolic alkalosis. HP:0001948 Abnormality of acid-base homeostasis