Ataxia Dysdiadochokinesis Dysdiadochokinesia Inability to perform rapid, alternating movements. Dysdiadochokinesis is generally related to a cerebellar lesion. Difficulty performing quick and alternating movements UMLS:C0234979 HP:0002075 A type of ataxia characterized by the impairment of the ability to perform rapidly alternating movements, such as pronating and supinating his or her hand on the dorsum of the other hand as rapidly as possible. HP:0002426 SNOMEDCT_US:23133003